Publications
| Articles: | 142 |
| Journal Impact total: | 1125 |
| Journal Impact/article: | 7.9 |
| Dec 2010 web of science | |
| Citation total: | 6795 |
| Citation/article: | 53 |
| Citation classics: | 36 |
| H factor: | 42 |
I.F. = Journal impact factor (1995 to 2010)
- Hoving, JC, F. Kirstein, N. Nieuwenhuizen, E. Hobeika, M. Reth and F. Brombacher 2011. Immunoglobulin E-producing B lymphocytes mediate colitis in BALB/c mice. Gastroenterology, in press. (IF 12). (1121.4).
- McFarlane, E., Carter, K.C., McKenzie, A., Kaye, P.M., Brombacher,F., and Alexander,J., 2011. Endogenous IL-13 plays a crucial role in liver granuloma maturation during Leishmania donovani infection via a macrophage independent mechanism. Journal of Infectious Diseases 204:36-43 (I.F.=5.2)
- Perkins, C., Yanase, N., Smulian, G., Gildea, L., Orekov, T., Potter, C., Brombacher, F., Wills-Karp, M., and Finkelman, F. D. 2011. Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice. J Exp Med. 208(4):853-67 (IF 15.1).
- Cook PC, Aynsley SA, Turner JD, Jenkins GR, Van Rooijen N, Leeto M, Brombacher F, Mountford AP. 2011. Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by th2 conditioning of dermal myeloid cells. PLoS Pathog. 7:e1001323. Epub 2011 Mar 17.
- Guler R, Afshar M, Arendse B, Parihar SP, Revaz-Breton M, Leitges M, Schwegmann A, Brombacher F. 2011. PKCδ regulates IL-12p40/p70 production by macrophages and dendritic cells, driving a type 1 healer phenotype in cutaneous leishmaniasis. Eur J Immunol. 41:706-15.
- Bryson KJ, Millington OR, Mokgethi T, McGachy HA, Brombacher F, Alexander. 2011. BALB/c Mice Deficient in CD4 T Cell IL-4Rα Expression Control Leishmania mexicana Load although Female but Not Male Mice Develop a Healer Phenotype.. J. PLoS Negl Trop Dis. 5:e930.
- Van der Ventel, M.L., N.E. Nieuwenhuizen, F. Kirstein1, C. Hikuam, M.F. Jeebhay, I. Swoboda, F. Brombacher*, and A.L. Lopata. 2011. Differential responses to natural and recombinant allergens 1 in a murine model of fish allergy. Mol Immunol. 48:637-46.
* corresponding author - Guler R, Parihar SP, Spohn G, Johansen P, Brombacher F* Bachmann MF. 2011. Blocking IL-1α but not IL-1β increases susceptibility to chronic Mycobacterium tuberculosis infection in mice. Vaccine. 29: 1339–1346. * corresponding author
- Marakalala, M.J., R. Guler, L. Matika, G. Murray, M. Jacobs, F. Brombacher, A. Gigliotti Rothfuchs, A. Sher and G.D. Brown. 2011. The Syk/ CARD9 coupled receptor Dectin 1 is not required for host resistance to Mycobacterium tuberculosis in mice. Microbes & Infection 13: 198-201.
- Horsnell WG, Vira A, Kirstein F, Mearns H, Hoving JC, Cutler AJ, Dewals B, Myburgh E, Kimberg M, Arendse B, White N, Lopata A, Burger PE, Brombacher F. 2011.. IL-4Ralpha-responsive smooth muscle cells contribute to initiation of T(H)2 immunity and pulmonary pathology in Nippostrongylus brasiliensis infections. Mucosal Immunol. 4:83-92 (IF 6.8)
- Dewals B, Hoving JC, Horsnell WG, Brombacher F. 2010. Control of Schistosoma mansoni egg-induced inflammation by IL-4-responsive CD4(+)CD25(-)CD103(+)Foxp3(-) cells is IL-10-dependent. Eur J Immunol. 40:2837-47 (IF 6)
- Kirstein F, Horsnell WG, Nieuwenhuizen N, Ryffel B, Lopata AL, Brombacher F., (2010). Anisakis-induced airway hyperresponsiveness is mediated by IFN-{gamma} in the absence of IL-4R{alpha}-responsiveness. Infect Immun. 78:4077-86 (I.F.= 3.7).
- Horsnell WG, Brombacher F. (2010). Genes associated with alternatively activated macrophages discretely regulate helminth infection and pathogenesis in experimental mouse models. Immunobiology. 215:704-.8 (IF = 3.6)
- Kirstein F, Horsnell WG, Kuperman DA, Huang X, Erle DJ, Lopata AL, Brombacher F. (2010). Expression of IL-4 receptor alpha on smooth muscle cells is not necessary for development of experimental allergic asthma. J Allergy Clin Immunol. 126:347-54. (IF 9)
- Uyttenhove C, Brombacher F, Van Snick J. (2010). TGF-beta interactions with IL-1 family members trigger IL-4-independent IL-9 production in mouse CD4 T cells. Eur J Immunol. Jun 10. [Epub ahead of print] (IF 6) (1061.3)
- Dewals BG, Marillier RG, Hoving JC, Leeto M, Schwegmann A, Brombacher F. (2010). IL-4Ralpha-independent expression of mannose receptor and Ym1 by macrophages depends on their IL-10 responsiveness. PLoS Negl Trop Dis. 4:e689. (IF 4.1)
- Hünig T, Lühder F, Elflein K, Gogishvili T, Fröhlich M, Guler R, Cutler A, Brombacher F. (2010). CD28 and IL-4: two heavyweights controlling the balance between immunity and inflammation. Med Microbiol Immunol. 199:239-46 (IF 2)
- Marillier RG, Brombacher TM, Dewals B, Leeto M, Barkhuizen M, Govender D, Kellaway L, Horsnell WG, Brombacher, F. (2010). IL-4R{alpha}-responsive smooth muscle cells increase intestinal hypercontractility and contribute to resistance during acute Schistosomiasis. Am J Physiol Gastrointest Liver Physiol. 298: 943-951. (IF 4.7)
- Jones, LA, Roberts F, Nickdel MB, Brombacher F, McKenzie AN, Henriquez FL, Alexander J, Roberts CW. (2010). IL-33 receptor (T1/ST2) signalling is necessary to prevent the development of encephalitis in mice infected with Toxoplasma gondii. Eur J Immunol. 40:426-26 (IF 6).
- Michels CE, Scales HE, Saunders KA, McGowan S, Brombracher F, Alexander J, Lawrence CE. (2009). Neither interleukin-4 receptor alpha expression on CD4+ T cells, or macrophages and neutrophils is required for protective immunity to Trichinella spiralis. Immunology. 128: e385-94. (IF = 3.6).
- Schäfer G, Guler R, Murray G, Brombacher F, Brown GD.(2009).The role of scavenger receptor B1 in infection with Mycobacterium tuberculosis in a murine model. PLoS One.4:e8448 (IF 4.3).
- Herbert DR, Yang JQ, Hogan SP, Groschwitz K, Khodoun M, Munitz A, Orekov T, Perkins C, Wang Q, Brombacher F, Urban JF Jr, Rothenberg ME, Finkelman FD. (2009). Intestinal epithelial cell secretion of RELM-{beta} protects against gastrointestinal worm infection. J Exp Med. 21:206:2947-57 (IF 15.1).
- Dewals, B., J. C. Hoving, M. Leeto, R. G. Marillier, U. Govender, A. J. Cutler†, W. G.C. Horsnell, F. Brombacher. (2009). IL-4Ra responsiveness of non-CD4 T cells contributes to resistance in Schistosoma mansoni infection investigated in pan-T cell-specific IL-4Rα-deficient mice. The Journal of American Pathology. 175:706-16 (IF 5.5). 1001
- Keating P, O'Sullivan D, Tierney JB, Kenwright D, Miromoeini S, Mawasse L, Brombacher F, La Flamme AC. (2009). Protection from EAE by IL-4Ralpha(-/-) macrophages depends upon T regulatory cell involvement. Immunol Cell Biol. 2009 Jun 2. (IF = 3)
- FANTOM Consortium, Suzuki H, Forrest AR, van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, Lassmann T, Ravasi T, Hasegawa Y, de Hoon MJ, Katayama S, Schroder K, Carninci P, Tomaru Y, Kanamori-Katayama M, Kubosaki A, Akalin A, Ando Y, Arner E, Asada M, Asahara H, Bailey T, Bajic VB, Bauer D, Beckhouse AG, Bertin N, Björkegren J, Brombacher F, Bulger E, Chalk AM, Chiba J, Cloonan N, Dawe A, Dostie J, Engström PG, Essack M, Faulkner GJ, Fink JL, Fredman D, Fujimori K, Furuno M, Gojobori T, Gough J, Grimmond SM, Gustafsson M, Hashimoto M, Hashimoto T, Hatakeyama M, Heinzel S, Hide W, Hofmann O, Hörnquist M, Huminiecki L, Ikeo K, Imamoto N, Inoue S, Inoue Y, Ishihara R, Iwayanagi T, Jacobsen A, Kaur M, Kawaji H, Kerr MC, Kimura R, Kimura S, Kimura Y, Kitano H, Koga H, Kojima T, Kondo S, Konno T, Krogh A, Kruger A, Kumar A, Lenhard B, Lennartsson A, Lindow M, Lizio M, Macpherson C, Maeda N, Maher CA, Maqungo M, Mar J, Matigian NA, Matsuda H, Mattick JS, Meier S, Miyamoto S, Miyamoto-Sato E, Nakabayashi K, Nakachi Y, Nakano M, Nygaard S, Okayama T, Okazaki Y, Okuda-Yabukami H, Orlando V, Otomo J, Pachkov M, Petrovsky N, Plessy C, Quackenbush J, Radovanovic A, Rehli M, Saito R, Sandelin A, Schmeier S, Schönbach C, Schwartz AS, Semple CA, Sera M, Severin J, Shirahige K, Simons C, St Laurent G, Suzuki M, Suzuki T, Sweet MJ, Taft RJ, Takeda S, Takenaka Y, Tan K, Taylor MS, Teasdale RD, Tegnér J, Teichmann S, Valen E, Wahlestedt C, Waki K, Waterhouse A, Wells CA, Winther O, Wu L, Yamaguchi K, Yanagawa H, Yasuda J, Zavolan M, Hume DA; Riken Omics Science Center, Arakawa T, Fukuda S, Imamura K, Kai C, Kaiho A, Kawashima T, Kawazu C, Kitazume Y, Kojima M, Miura H, Murakami K, Murata M, Ninomiya N, Nishiyori H, Noma S, Ogawa C, Sano T, Simon C, Tagami M, Takahashi Y, Kawai J, Hayashizaki Y. (2009). The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics 41:553-62 (IF 22)
- Brombacher F, Arendse B, Peterson R, Hölscher A, Hölscher C. (2009). Analyzing classical and alternative macrophage activation in macrophage/neutrophil-specific IL-4 receptor-alpha-deficient mice. Methods Mol Biol. 2009;531:225-52 (IF 4)
- Steenwinckel V, Louahed J, Lemaire MM, Sommereyns C, Warnier G, McKenzie A, Brombacher F, Van Snick J, Renauld JC. (2009). IL-9 promotes IL-13-dependent paneth cell hyperplasia and up-regulation of innate immunity mediators in intestinal mucosa. J Immunol. 182:4737-43 (I.F.= 7.4).
- Nieuwenhuizen N, Herbert DR, Brombacher F, Lopata AL. (2009) Differential requirements for interleukin (IL)-4 and IL-13 in protein contact dermatitis induced by Anisakis. Allergy. 64:1309-18 (IF 4)
- Stenzel W, Müller U, Köhler G, Heppner FL, Blessing M, McKenzie AN, Brombacher F, Alber G. (2009) IL-4/IL-13-dependent alternative activation of macrophages but not microglial cells is associated with uncontrolled cerebral cryptococcosis. Am J Pathol. 174:486-96 (IF 5.5).
- Muller, U. W. Stenzel, G. Koehler, T. Polte, M. Blessing, A. Mann, D. Piehler, F. Brombacher, G. Alber. (2008). A gene-dosage effect for interleukin-4 receptor alpha-chain expression has an impact on Th2-mediated allergic inflammation during bronchopulmonary mycosis. J. Infect. Dis 198:1714-21. (IF 5.5)
- Horsnell, W.G., F. Brombacher. (2008) Key roles for specific and nonspecific antibody in intestinal nematode expulsion. Cell Host Microbe 16:303-5 (expected IF 12)
- Barkhuizen, M., S Magez, B Ryffel and F Brombacher. (2008). Interleukin-12p70 Deficiency Increases Survival and Diminishes Pathology in Trypanosoma congolense Infection. J. Infect. Dis 198:1284-91. (IF 5.5)
- Mearns H, W GC Horsnell, J C Hoving, B. Dewals, A. J. Cutler, F. Kirstein, E Myburgh, B. Arendse and F. Brombacher. (2008). IL-4 promoted T-helper 2 responses enhance Nippostrongylus brasiliensis induced pulmonary pathology. Infect. & Immunity, 76:5535-42 (I.F.= 3.7).
- Barbi, J, F. Brombacher, AR Satoskar. (2008). T cells from Leishmania major-susceptible BALB/c mice have a defect in efficiently up-regulating CXCR3 upon activation. J. Immunol. 181:4613-20 (I.F.= 7.4).
- Magez, S., A. Schwegmann, R. Atkinson, F. Claes, M. Drennan, P. De Baetselier, and F. Brombacher. (2008). The role of B-cells and IgM antibodies in paratemia, anemia, and VSG switching in Trypanosoma brucei-infected mice. PLoSpathogen, 4:e000122 (I.F.= 9.6).
- Schwegmann, A & F. Brombacher. (2008). Host-directed drug targeting of factors hijacked by pathogens. Science Signaling 1:29-36. (expected IF 15)
- Marillier, R. G., C. Michels, E M Smith, L Fick, M Leeto, B Dewals, W GC Horsnell , F Brombacher. (2008). IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections. BMC Immunology. 9:11-18. (IF 3)
- Myburgh E, Horsnell WG, Cutler AJ, Arendse B, Kubo M, Brombacher F. (2008). Murine IL-4 is able to signal via chimeric human IL-4Ralpha/mouse gamma-chain receptor. Mol Immunol. 45:1327-36. (IF 4)
- Barkhuizen, M, S. Magez, R.A. Atkinson, & F. Brombacher. (2007). Interleukin 12p70-dependendent IFN-g production is crucial for resistance in African Trypanosomiasis. J Infect Dis. 1196:1253-60 (IF 5.5) 887.9
- Schwegmann A, Guler R, Cutler AJ, Arendse B, Horsnell WG, Flemming A, Kottmann AH, Ryan G, Hide W, Leitges M, Seoighe C, Brombacher F. (2007). Protein kinase C {delta} is essential for optimal macrophage-mediated phagosomal containment of Listeria monocytogenes. Proc Natl Acad Sci U S A. 104:16251-6. (I.F.= 10.4)
- Muller U, Stenzel W, Kohler G, Werner C, Polte T, Hansen G, Schutze N, Straubinger RK, Blessing M, McKenzie AN, Brombacher F, Alber G. (2007). IL-13 Induces Disease-Promoting Type 2 Cytokines, Alternatively Activated Macrophages and Allergic Inflammation during Pulmonary Infection of Mice with Cryptococcus neoformans. J Immunol. 179(8):5367-77 (I.F.= 7.4).
- Loke P, Gallagher I, Nair MG, Zang X, Brombacher F, Mohrs M, Allison JP, Allen JE. (2007). Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection. J Immunol. 179(6):3926-36 (I.F.= 7.4).
- Nieuwenhuizen, D. R. Herbert, N., A. L. Lopata, F. Brombacher (2007). CD4+ T Cell-Specific Deletion of IL-4 Receptor {alpha} Prevents Ovalbumin-Induced Anaphylaxis by an IFN-{gamma}-Dependent Mechanism. J. Immunol. 179: 2758-65 (I.F.= 7.4).
- S. Magez, M. Radwanska, M. Drennan, L. Fick, T.N. Baral, N. Allie, M. Jacobs, S. Nedospasov, F. Brombacher, B. Ryffel, P.D. Baetsellier (2007). Tumor Necrosis Factor (TNF) Receptor-1 (TNFp55) Signal Transduction and Macrophage-Derived Soluble TNF Are Crucial for Nitric Oxide-Mediated Trypanosoma congolense Parasite Killing. J. Infect. Dis. 196:954-62 (I.F. 5.5).
- Odegaard, J.I., R.E. Ricardo-Gonzalez, M.H. Goforth, C.R. Morel, V. Subramanian, L. Mukundan, A. Red Eagle, D. Vats, F. Brombacher A.W. Ferrante, A. Chawla. (2007). Macrophage-specific PPARg controls alternative activation and improves insulin resistance. Nature 447:1116-20 (I.F.= 27)
- Spohn, G., R. Guler, P. Johansen, I. Keller, M. Jacobs, M. Beck, F. Rohner, M. Bauer, K. Dietmeier, T.M. Kündig, G.T. Jennings, F. Brombacher, and M.F. Bachmann (2007) A VLP-based Vaccine against Soluble TNFa Protects from Arthritis without Inducing Reactivation of Tuberculosis. J. Immunol. 178:7450-57 (I.F.= 7.4).
- Radwanska, A. Cutler, M., C. Hoving, S. Magez, C. Holscher, A. Bohms, B. Arendse, R. Kirsch, T. Hunig, J. Alexander, J. Kaye & F. Brombacher (2007). Deletion of IL-4Ralpha on CD4 T cell renders BALB/c mice resistant to Leishmania major phenotype. PLoSpathogen, 3:e68-79. (I.F.= 9.6)
- Baral, TN, De Baetselier P, Brombacher F, Magez S. (2007). Control of Trypanosoma evansi Infection Is IgM Mediated and Does Not Require a Type I Inflammatory Response. J Infect Dis. 195:1513-20 (I.F. 5.5).
- Baschuk, R., O. Utermoehlen, N. Gugel, G. Warnecke, U. Karow, D. Paulson, F. Brombacher, M. Kroehnke, W. Deppert (2007). Interleukin-4 impairs granzyme-mediated cytotoxicity of Simian virus 40 large tumor antigen-specific CTL in BALB/c mice. Cancer Immunol Immunother. 56:1625-36 (IF approx 3)
- Waisman A, Kraus M, Seagal J, Ghosh S, Melamed D, Song J, Sasaki Y, Classen S, Lutz C, Brombacher F, Nitschke L, Rajewsky K. (2007). IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Iga/b. J Exp Med. 4:747-58 (I.F.= 15.1).
- Horsnell, W. G. C., A. J. Cutler, C. Hoving, H. Mearns, E. Myburg, B. Arendse, F. D. Finkelman, G. K. Owens, D. Erle, and F. Brombacher (2007). Delayed goblet cell hyperplasia and worm expulsion in smooth muscle cell specific IL-4Ra deficient mice. PLoSpathogen, 162:7302-7308. (I.F.= 9.6)
- Cao Y, Brombacher F, Tunyogi-Csapo M, Glant TT, Finnegan (2007). Interleukin-4 regulates proteoglycan-induced arthritis by specifically suppressing the innate immune response. Arthritis Rheum. 3:861-70. (IF approx 4)
- Kleinschek MA, Owyang AM, Joyce-Shaikh B, Langrish CL, Chen Y, Gorman DM, Blumenschein WM, McClanahan T, Brombacher F, Hurst SD, Kastelein RA, Cua DJ. (2007) IL-25 regulates Th17 function in autoimmune inflammation. J Exp Med. 204:161-70. (I.F.= 15.1, 74 citations, 8.09).
- Schnyder-Candrian S, Togbe D, Couillin I, Mercier I, Brombacher F, Quesniaux V, Fossiez F, Ryffel B, Schnyder B. (2006). Interleukin-17 is a negative regulator of established allergic asthma. J Exp Med. 203:2715-25 (I.F.= 15.1, 86 citations, 8.09).
- Leeto, M., D. R. Herbert, R. Mariller, A. Schwegmann, L. Fick, and F. Brombacher (2006). TH1-Dominant Granulomatous Pathology Does Not Inhibit Fibrosis or Cause Lethality during Murine Schistosomiasis. J. American Pathology. 169:1701-12. (I.F. = 9)
- Galina G., L. Dolcetti, P. Serafini, C. De Santo, I. Marigo, M.P. Colombo, G. Basso, F. Brombacher, I. Borrello, P. Zanoveilo, S. Bicciato, V. Bronte (2006). Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J. Clin. Invest., 116:2777(I.F. = 13, 122 citations, 8.09). 6,266
- Misson P, Brombacher F, Delos M, Lison D, Huaux FA. (2006). Type-2 immune response associated with silicosis is not instrumental in the development of the disease. Am J Physiol Lung Cell Mol Physiol. 292:L107-13 (IF 3)
- Michels, C., P. Goyal, N. Nieuwenhuizen and F. Brombacher (2006). Infection with Syphacia obvelata (pinworm) induces protective Th2 immune responses and influences Ovalbumin-induced allergic reactions. Inf. & Immun. 74:5926-32. (I.F.= 3.7).
- Balic A, Harcus YM, Taylor MD, Brombacher F, Maizels RM. (2006). IL-4R signaling is required to induce IL-10 for the establishment of Th2 dominance. Int Immunol., 18:1421-31. (I.F.= 4.3)
- Nieuwenhuizen, N., A. L. Lopata, M. F. Jeebhay, D. R. Herbert, T. G.Robins, F. Brombacher (2006). The nematode Anisakis, hidden in fish, can cause occupational allergy. J Allergy Clin Immun, 117:1098. (I.F. = 9)
- Magez S, Radwanska M, Drennan M, Fick L, Baral TN, Brombacher F, Baetselier PD. (2006). Interferon- gamma and Nitric Oxide in Combination with Antibodies Are Key Protective Host Immune Factors during Trypanosoma congolense Tc13 Infections. J Infect Dis.193:1575-1583. (I.F. = 5.5)
- Ghassabeh, G., P. De Baetselier, L. Brys, W. Noël, J. A. Van Ginderachter, S. Meerschaut, A. Beschin, F. Brombacher and G. Raes (2006). Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo during different pathologies. Blood, 108:575-83. (I.F. = 11; , 52 citation Dec2010)
- Pace, L., S. Rizzo, C. Palombi, F. Brombacher, G. Doria. (2006). IL-4-induced protection of CD4+CD25- Th cells from CD4+CD25+ regulatory T cell-mediated suppression. J. Immunol. 176:3900-04. (I.F.= 7.4).
- Cutler, A. & F. Brombacher (2005) Cytokine Therapy. Ann NY Acad Sci. 1056:16-29. (I.F. 1.5)
- Hölscher, C., B. Arendse, A. Schwegmann, Elmarie Myburgh & F. Brombacher (2006). Impairment of alternative macrophage activation delays cutaneous leishmaniasis in non-healing BALB/c mice. J. Immunol. 176:1115-21 (I.F. = 7.4).
- Couper KN, Roberts CW, Brombacher F, Alexander J, Johnson LL. (2005) Toxoplasma gondii-specific immunoglobulin M limits parasite dissemination by preventing host cell invasion. Infect Immun. 73:8060-8. (I.F.= 3.7).
- Kuperman, D.A., X. Huang, L. Nguyenvu, C. Hölscher, F. Brombacher & D.J. Erle (2005).IL-4 receptor signaling in Clara cells is required for allergen-induced mucus production. J. Immunol. 175:3746-52 (I.F.= 7.4).
- Drennan, M., B. Stijlemans, J. Van Den Abbeele, V. Quesniaux, F. Brombacher, P. De Baetselier, B. Ryffel & S. Magez. (2005). The induction of a type 1 response following a Trypanosoma brucei infection is MyD88-dependent. J. Immunol. 175: p. 2501-2509 (I.F. = 7.4)
- Couper KN, RS. Phillips, F. Brombacher, J. Alexander (2005). Parasite-specific IgM plays a significant role in the protective immune response to asexual erythrocytic stage Plasmodium chabaudi AS infection. Parasite Immunol. 27:171-80. (I.F. ca 1.5).
- Brys, L., A. Beschin, G. Raes, G.G. Hassanzadeh, W. Noël, J. Brandt, F. Brombacher, P. De Baetselier. (2005). Reactive Oxygen Species and 12/15-lipoxygenase contribute to the anti-proliferative capacity of alternatively activated myeloid cells elicited during helminth infection. J. Immunol., 174:6095-6104. (I.F.= 7.4, 50 citation Dec2010). 544.6
- Arendse, B., Van Snick, J., & Brombacher F. (2005). Interleukin-9 is a susceptibility factor in Leishmania major infection by promoting detrimental Th2/type2 responses. J. Immunol. 174:2205-2211. (I.F.= 7.4).
- Arras M, Louahed J, Heilier JF, Delos M, Brombacher F, Renauld JC, Lison D, Huaux F. (2005). IL-9 Protects against Bleomycin-Induced Lung Injury: Involvement of Prostaglandins. Am J Pathol.166(1):107-15. (I.F. = 8)
- Raes G, Brys L, Dahal BK, Brandt J, Grooten J, Brombacher F, Vanham G, Noel W, Bogaert P, Boonefaes T, Kindt A, Van den Bergh R, Leenen PJ, De Baetselier P, Ghassabeh GH. (2004). Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation. J. Leukoc. Biol. 77:321-7. (I.F. = 4.5; , 58 citation Dec2010) 5,180
- Uyttenhove, C., Arendse, Stroobant, B., Brombacher, F., Van Snick, J. (2004). Anti-IL-12 auto-vaccination: a treatment for experimental autoimmune encephalomyelitis at the expense of reduced cell-mediated immunity. J. Immunol. 34:3572-81. (I.F.= 7.4).
- McDonald S.A.C, O'Grady J.E., Bajaj-Elliott M., Notley C.A., Alexander J., Brombacher F. & McDonald V. (2004). IL-4 confers protection against the early acute phase of Cryptosporidium parvum infection by promoting Th1 cytokine expression. J Inf. Dis. 190:1019-25. (I.F. 5.5).
- Nickel, M.B, R. E. Lyons, F. Roberts, F. Brombacher, C. A. Hunter, J. Alexander, C. W. Roberts. 2004. Intestinal pathology during acute toxoplasmosis is IL-4-dependent and unrelated to parasite burden. Parasite Immunol. 26:75-82. (I.F. ca 1.5).
- Herbert, D. R., C. Hölscher, M. Mohrs, B. Arendse, A. Schwegmann, M. Radwanska, M. Leeto, R. Kirsch, P. Hall, H. Mossmann, B. Claussen, I. Förster & F. Brombacher. 2004. Alternative macrophages activation is essential for survival during schistosomiasis and downmodulates T Helper 1 responses and immunopathology. Immunity. 20:623-35. (I.F.=20; 124 citations, 8.09).
- Seki, N., M. Miyazaki, W. Suzuki, K. Hayashi, K. Arima, E. Myburgh, K. Izuhara, F. Brombacher, M. Kubo. 2004. Role of IL-4-induced GATA-3 expression as a time-dependent instruction switch on cytokine expression in helper T cell differentiation. J. Immunol., 172:6158-66. (I.F.= 7.4).
- Cunningham, A., K. Serre, K-M. Toellner, M. Khan, J. Alexander, F. Brombacher, I.C.M. MacLennan. 2004. Pinpointing IL-4-independent and IL-4-influenced acquisition and maintenance if Th2 activity by CD4 T cells. Europ. J. Immunol. 34:686-94. (I.F.=6.0)
- Han, S., Zhang, X., Finkelman, F.D., Brombacher, F., and Zheng, B. 2004. IgD+IgM- B cells Mount Immune Response that Exhibit Altered Antibody Repertoire. Europ. J. Immunol. 34:661-8. (I.F.=6.0)
- Magez, S., C. Truyens, M. Merimi, M. Radwanska, B. Stijlemans, P. Brouckhaert, F. Brombacher, E. Pays, P.D. Baetselier. 2004. P75 Tumor Necrosis Factor-Receptor Shedding Occurs as a Protective Host Response during African Trypanosomiasis. J. Infect. Dis. 189:527-539 (I.F. 5.5 ).
- Saeftel, M., A. Kruger, S. Ariens, P. Racz, B. Fleischer, F. Brombacher, A. Hoerauf. 2004. Mice Deficient in Interleukin-4 (IL-4) or IL-4 Receptor alpha Have Higher Resistance to Sporozoite Infection with Plasmodium berghei (ANKA) than Do Naive Wild-Type Mice. Inf. & Immun., 72(1):322-331 (I.F.= 3.7).
- Stager, S., J. Alexander, M. Botto, A. C. Kirby, N. Van Rooijen, D. F. Smith, F. Brombacher and P. M. Kaye. 2003. Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T cell responses. Nature Medicine, 9:1287-92 (I.F. 27; 66 citations, 8.09).
- Linehan, S. A., P. S. Coulson, R. A. Wilson, A. P. Mountford, F. Brombacher, L. Martínez-Pomares and S. Gordon. 2003. IL-4 receptor signaling is required for mannose receptor expression by macrophages recruited to granulomata but not resident cells in mice infected with Schistosoma mansoni. Lab. Invest. 83:1223-31 (I.F. around 2).
- F. Brombacher, R. Kastelein, G. Alber. 2003. Novel IL-12 family members uncovered in regulation of Th1 responses. Trends Immunol. 24:207-212 (I.F. =7; 133 citations, 8.09).
- Stager, S., Smith, D.F., Brombacher, F., Alexander, J., Kaye, P.M. 2003. Immunisation with a stage-regulated surface protein from Leishmania donovani protects wild-type but not IL-4 or IL-4Ra deficient mice against visceral leishmaniasis. Infec & Immun. 71(8):4804-7 (I.F.= 3.7).
- Herrmann, O., V. Tarabin, S. Suzuki, N. Attigah, I. Coserea, A. Schneider, J. Vogel, S. Prinz, S. Schwab, H. Monyer, F. Brombacher, M. Schwanninger. 2003. Regulation of body temperature and neuroprotection by endogenous Interleukin-6 in cerebral ischemia. J. Cereb. Blood Flow Metab. 4:406-415 (I.F. 2, , 51 citation Dec2010 ).
- Volkmann, L., O. Bain, M. Saeftel, S. Specht, K. Fischer, F. Brombacher, K.I. Matthaei, A. Hoerauf. 2003. Murine filariasis: interleukin 4 and interleukin- 5 lead to containment of different worm developmental stages. Med. Microbiol. & Immunol. 192: 23-31. (I.F. = 1.6).
- Fincham, J. E., M. B. Markus, F. Brombacher. 2002. Vaccination against helminths: influence on HIV/AIDS and TB. Trends Parasitol. 18:385-6. (I.F. =7)
- Noël W., Gh. Hassanzadeh, G. Raes, B. Namangala, I. Daems, L. Brys, F. Brombacher, P. De Baetselier and A. Beschin. (2002). Infection stage-dependent contribution of alternatively activated macrophages to resistance/susceptibility to Trypanosoma congolense. Infect. & Immun., 70:6180-87 (I.F.= 3.7).
- Alexander, J., Brombacher, F., McGachy, A., Scott, P., McKenzie, A.N.J., Walker, W., and Carter, K.C. 2002. An essential role for IL-13 in maintaining a non-healing response following Leishmania mexicana infection. Europ. J. Immunol. 32:2923. (I.F.=6.0).
- Kopf, M., B., F. Brombacher, M. F. Bachmann. 2002. Critical role of secreted IgM in protection against pulmonary influenza virus infection. Europ. J. Immunol. 32:2229-36. (I.F.= 6.0).
- Raes, G., P. De Baetselier, W. Noël, A. Beschin, F. Brombacher and Gh. Hassanzadeh. 2002. Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages. J. Leukoc. Biol 71:597-602. (I.F. = 4.5; cited up to 2007: 59) 3,845
- Hölscher, C. R. A. Atkinson, B. Arendse, N. Brown, E. Myburgh, G. Alber, F. Brombacher 2001. A protective and agonistic function of interleukin-12p40 homodimer in mycobacterial infection. J. Immunol, 167:6957-66. (I.F.= 7.4, 111 citations, 8.09).
- Eriksson, U., M. O. Kurrer, W. Seebald, F. Brombacher, M. Kopf. 2001. Dual role of IL-12/IFN-gamma axis in the development of autoimmune: Induction by IL-12 and protection by IFN-gamma. J. Immunol. 167:5464-5469 . (I.F.= 7.4; , 57 citation Dec2010).
- Grunewald, S. M., M. Teufel, K. Erb, A. Nelde, M. Welte, F. Brombacher, E. B. Bröcker, W. Sebald, A. Duschl. 2001. Upon prolonged allergen exposure IL-4 and IL-4Ralpha knockout mice produce specific IgE leading to anaphylaxis. Int Arch Allergy Immunol. 125:322-8. (I.F.= 2).
- Mueller, U., G. Koehler, H. Mossmann, G. A. Schaub, G. Alber, J. Di Santo, F. Brombacher, C. Hoelscher. 2001. IL-12-Independent IFN-gamma Production by T Cells in Experimental Chagas' Disease Is Mediated by IL-18. J. Immunol. 167:3346-53. (I.F.= 7.4)
- Biedermann, T., R. Mailhammer, A. Mai, C. Sander, A. Ogilvie, F. Brombacher, K. Maier, A. D. Levine, M. Röcken. 2001. Reversal of established delayed type hypersensitivity reactions following therapy with IL-4 or antigen-specific Th2 cells. Europ. J. Immunol. 31:1582-91. (I.F.= 6.0).
- Fort, M. M., R. Lesley, N. J. Davidson, S. Menon, , F. Brombacher, N. W. Leach, D. A. Rennick. 2001. Interleukin-4 exacerbates disease in a Th1 T cell transfer model of colitis. J. Immunol. 166:2793-2800 (I.F.= 7.4, 50 citations, 8.09).
- Nickdel, M. B., F. Roberts, F. Brombacher, J. Alexander, C. W. Roberts. 2001. A counter-protective role for IL-5 during acute Toxoplasma gondii infection. Inf.&Immun. 69:1044-69 (I.F.= 3.7).
- Bregenholt, C., P. Berche, F. Brombacher, J. Di Santo. 2001. Conventional ab Tcells are sufficient for innate and adaptive immunity against enteric Listeria. monocytogenes. J. Immunol, 166:1871-76 (I.F.= 7.4).
- Mountford, A. P., K. G. Heal, P. S. Coulson, F. Brombacher. 2001. Signaling via IL-4 receptor alpha chain is required for protective vaccination against murine schistosomiasis. Inf. & Immun 69:228-236 (I.F.= 3.7)
- Aebischer, T., S. Laforsch, R. Hurwitz, F. Brombacher, T. F. Meyer. 2001. Immunity against Helicobacter pylori infection in mice: a role for interleukin-4 receptor a chain and sex? Inf.&Immun. 69:556-558 (I.F.= 3.7) 3,276
- Alexander, J., K.C. Carter., N. Al-Fasi, A. Satoskar, F. Brombacher. 2000. Endogenous IL-4 is necessary for effective drug therapy against visceral leishmaniasis. Europ. J. Immunol. 30:2935-43 (I.F.= 6.0)
- Brombacher, F. 2000. The role of interleukin-13 in infectious diseases and allergy. BioEssays. 22:646-656 (I.F. = 7.3; 62 citations, 12.10). 321.63
- Okano, M., A. R. Satoskar, M. Abe, D. A. Harn, M. Okana, K. Nishizaki, Y. Takeda, T. Yoshino, F. Brombacher, AA. Satoskar. 2000. Interleukin-4-independent production of Th2 cytokines by nasal lymphocytes and nasal eosinophilia in murine allergic rhinitis. Allergy. 55:723-31. (I.F.= 0.9)
- Houston, K. M., E. H. Wilson, L. Eyres, F. Brombacher, M. M. Harnett, J. Alexander, W. Harnett. 2000. Presence of phosphorylcholine on a filarial nematode protein influences immunoglobulin G subclass response to the molecule and by an interleukin-10-dependent mechanism. Inf.&Immun. 68:5466-68, (I.F.= 3.7)
- Hölscher, C., M. Mohrs, W. J. Dai, G. Köhler, B. Ryffel, G. A. Schaub, H. Mossmann, F. Brombacher. 2000. TNF-a-mediated toxic shock syndrome in Trypanosoma cruzi-infected IL-10 deficient mice. Inf. & Immun. 68:1773-80 .(I.F.= 3.7, 59 citations, 12.10).
- Mohrs, M., C. Hölscher, and F. Brombacher. 2000. IL-4Ra deficient Balb/c mice have an unimpaired Th2 polarization in response to Leishmania major infection. Inf.&Immun. 68:1773-80.(I.F.= 3.7)
- Ochsenbein, A. F., T. Fehr, C. Lutz, M. Suter, F. Brombacher, H. Hengartner, R. M. Zinkernagel. 1999. Control of early viral and bacterial distribution and disease by natural antibodies. Science. 286:2156-59 (I.F.= 23, 330 citations, 8.09).
- Brewer, J., M. Conacher, M. C. A. Hunter, M. Mohrs, F. Brombacher, J. Alexander. 1999. Aluminium hydroxide adjuvant initiates strong antigen specifc Th2 responses in the absence of IL-4 and IL-13 mediated signaling. J. Immunol. 163:6448-54 (I.F.= 7.4, 123 citations, 8.09).
- Mohrs, M., B. Ledermann, G. Koehler, A. Dorfmueller, A. Gessner, F. Brombacher. 1999. Differences between IL-4 and IL-4Ra deficient mice in chronic Leishmaniasis reveal a protective role for IL-13 receptor signalling. J. Immunol. 162:7302 (I.F.= 7.4; 111 citations, 8.09).
- Vink, A., M-C. Many, G. Warnier, F. Brombacher, J-C. Renauld. 1999. IL-9-induced in vivo expansion of the B-1 lymphocyte population. J. Exp. Med. 189:1413-23 (I.F.= 15.1; 62 citations, 8.09).
- Cohn, L., R. J. Homer, A. H. MacLeod, F. Brombacher, M. Mohrs, K. Bottomly. 1999. Th2 induced airway mucus production is dependent on IL-4Ra, but not on eosinophils. J. Immunol. 162:6178-83. (I.F.= 7.4; 156 citations, 8.09).
- Brombacher, F., A. Dorfmüller, J. Magram, J. Ferrante, W. J. Dai, G. Köhler, A. Wunderlin, K. Palmer, M. K. Gately and G. Alber. 1999. Interleukin-12 is dispensable for protective immunity against low doses of Listeria monocytogenes. Intern. Immun. 11:325 (I.F.= 3.8; 56 citations 02.10)
- Grünig, G., M. Warnock, A. E. Wakil, R. Venkayya, F. Brombacher, D. M. Rennick, D. Sheppard, M. Mohrs, D. D. Donaldson, R. M. Locksley, D. B. Corry. 1998. Interleukin 13 and interleukin 4 mediate the asthmatic phenotype through interleukin 4 receptor a. Science, 282:2261-63. (I.F.= 23; 949 citations, 8.09).
- Bozza, M., M. B. P. Soares, P. T. Bozza, A. Satoskar, T. G. Diacovo, F. Brombacher, R. G. Titus, C. B. Shoemaker, J. R. David. 1998. The selective PACAP-type I receptor agonist Maxadilan from sand fly saliva protects mice against lethal endotoxemia. Eur. J. Immunol. 28: 3120-27. (I.F.= 6.0)
- Andersson, A., W. J. Dai, J. P. Di Santo, F. Brombacher. 1998. Innate immunity to Listeria in the absence of NK cells. J. Immunol, 161:5600 (I.F.= 7.4)
- Coyle, A.J., G., Köhler, S. Tsuyuki, F. Brombacher, and M., Kopf. 1998. Eosinophils are not required to induce airway hyperresponsiveness after nematode infection. Eur. J. Immunol. 28:2640-7 (I.F.= 7.4)
- Lutz, C., B. Ledermann, M. Kosco-Vilbois, A. F. Ochsenbein, R. M. Zinkernagel, G. Köhler, F. Brombacher. 1998. IgD can largely substitute for loss of IgM function in B cells. Nature 393:797-801(I.F.= 27.0; 58 citations, 8.09).
- Barner, M., M. Welte, F. Brombacher, M. Kopf. 1998. Differences between IL-4Ra and IL-4 deficient mice reveal a novel role of IL-13 in the regulation of T helper 2 cells and protection to nematode infection. Curr. Biol. 8:669-72 (I.F.= 12.0; 109 citations, 8.09).
- Grunewald, S. M., A. Werthmann, B. Schnarr, C. E. Klein, E. B. Bröcker, M. Welte, F. Brombacher, W. Sebald, A. Duschl. 1998. Inhibition of the IL-4/IL-13 receptor system by a murine IL-4 mutant (QY) prevents the humoral response to allergen and the development of type I allergy in vivo. J. Immunol. 160:4004-9. (I.F.= 7.4; 81 citations, 8.09).
- Hölscher, C., G. Köhler, U. Muller, H. Mossmann, G. A. Schaub, F. Brombacher. 1998. Defective NO effector functions lead to mortality in IFN-gR- and iNOS-deficient mice during acute infection withTrypanosoma cruzi. Infect. & Immun. 66:1208-15 (I.F.= 3.7; 118 citations, 8.09).
- Alexander, J, H. Jebbari, H. Blüthmann, F. Brombacher, C. W. Roberts. The role of IL-4 in adult acquired and congenital toxoplasmosis. 1998. Intern. J. Parasit., 28:113-20 (I.F.= 1.0)
- Satoskar, A., F. Brombacher, W. J. Dai, I. McInnes, F. Y. Liew, J. Alexander and W. Walker. 1997. Severe combined immunodeficient mice reconstituted with IL-4 deficient lymphocytes but not immunocompetent lymphocytes are resistant to cutanous leishmaniosis. J. Immunol. 159:5005-13 (I.F.= 7.4)
- Noben-Trauth, N., L. D. Shultz, F. Brombacher, J. F. Urban, H. Gu, W. E. Paul. 1997. An Interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice. Proc. Natl. Acad. Sci. USA. 94:10838-43 (I.F.= 10.5; 181 citations, 8.09).
- Monteyne, P., J. C. Renauld, J. Van Broeck, D. W. Dunne, R. Kühn, F. Brombacher and J.-P. Coutelier. 1997. IL-4 independent regulation of in vivo IL-9 expression. J. Immunol. 159:2616-23. (I.F.= 7.4)
- Dai, W. J., W. Bartens, G. Köhler, M. Hufnagel, M. Kopf and F. Brombacher. 1997. Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes infected IFN-g -receptor deficient mice. J. Immunol. 158: 5297. (I.F.= 7.4; 99 citations, 8.09).
- Nielsen, P. J., B. Lorenz, A. M. Müller, R. H. Wenger, F. Brombacher, M. Simon, T. Von der Weid, H. Mossmann and G. Köhler. 1997. Altered erythrocytes and a leaky block in B-cell development in CD24/HSA-deficient mice. Blood 89:1058. (I.F.= 12.0)
- Dai, W. D., G. Köhler and F. Brombacher. 1997. Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10 deficient mice. J. Immunol. 158:2259. (I.F.= 7.4; 93 citations, 8.09).
- Kopf, M., F. Brombacher, G. Kienzle, K.-H. Widmann, K. Lefranc, C. Humborg, B. Ledermann and W. Solbach. 1996. IL-4-deficient mice without elevating Th1 responses resist infection with Leishmania major. J. Exp. Med. 184:1127. (I.F.= 15.1; 172 citations, 8.09).
- Battegay, M., P. Fiedler, U. Kalinke, F. Brombacher, R. M. Zinkernagel, H-H. Peter, G. Köhler, H. Eibel. 1996. Non-tolerant B cells cause autoimmunity in anti-CD8 IgG2a-transgenic mice. Eur. J. Immunol. 26:250. (I.F.= 6.0) 748
- Brombacher, F. and M. Kopf. 1996. Innate versus acquired immunity in Listeriosis. Res. Immunol. 147:505. (I.F.= 1.3)
- Kopf, M., F. Brombacher, P. Hodkin, E. Milbourne, W. J. Dai, C. Beam, I. G. Young, G. Köhler and K. Matthaei. 1996. Developmental defect in CD5+ B-1 cells and lack of eosinophilia in IL-5 deficient mice. Immunity 4:15. (I.F. = 20; 326 citations, 8.09).
- Kopf, M., A. Ramsay, F. Brombacher, H. Baumann, G. Freer, C. Galanos, R. J. Gutierrez and G. Köhler. 1995. Pleiotropic defects of IL-6-deficient mice including early hematopoiesis, T and B cell function, and acute phase responses. Ann. N.Y. Acad. Sciences 762:308. (I.F.= 0.8; 54 citations, 12.10)
- Kopf, M., G. LeGros, A. Coyle, M. Kosco-Vilbois and F. Brombacher. 1995. Immune responses of IL-4, IL-5, IL-6 deficient mice. Immunol. Rev. 148:45. (I.F.= 5.9; 86 citations, 8.09).
- Brombacher, F., T. Schäfer, U. Weissenstein, C. Tschopp, E. Andersen, K. Bürki and G. Baumann. 1994. IL-2 promoter-driven lacZ expression as a monitoring tool for IL-2 expression in primary T cells of transgenic mice. Intern. Immunol. 6:189. (I.F.= 4.3)
- Eibel, H., F. Brombacher and G. Köhler. 1992. Analysis of B-cell tolerance in mice expressing transgenic anti-CD8.2 immunoglobulin M molecules. Res. Immunol. 143:276. (I.F.= 1.3)
- Brombacher, F., G. Köhler and H. Eibel. 1991. B cell tolerance in mice transgenic for anti-CD8 immunoglobulin m chain. J. Exp. Med. 174:1335. (I.F.= 15.1)
- Berling, B., F. Kolbinger, F. Grunert, J. A. Thompson, F. Brombacher, F. Buchegger, K. S. von Kleist, and W. Zimmermann. 1990. Cloning of a carcino- embryonic antigen gene family member expressed in leukocytes of chronic myeloid leukemia patients and bone marrow. Cancer Res. 50:6534. (I.F. = 5.2; 86 citations, 8.09).
- Brombacher, F., M. C. Lamers, G. Kohler and H. Eibel. 1989. Elimination of CD8(+) thymocytes in transgenic mice expressing an anti-Lyt2.2 immunoglobulin heavy chain gene. EMBO J.8:3719. (I.F. = 12.6)
- Kolbinger, F., K. Schwarz, F. Brombacher, K. S. von Kleist, and F. Grunert. 1989. Expression of an NCA cDNA in NIH/3T3 cells yields a 110K glycoprotein, which is anchored into the membrane via glycosyl-phosphatidylinositol. Biochem. Biophys. Res. Comm. 161:1126. (I.F. = 3.6)
Books/Chapters/Commentaries
Macrophages and Dendritic Cells. Methods and Protocols. Editor N.E. Reiner Title: Analyzing classical and alternative macrophage activation in macrophage/neutrophil-specific IL-4 receptor-alpha-deficient mice. F. Brombacher, B Arendse, R. Peterson, A. Hoelscher, C. Hoelscher. Pp 225-252 Humana Press (2009) ISBN: 978-1-58829-972-7
Advances in the Immunobiology of Parasitic Diseases, Editor: L. I. Terrazas Title: Alternatively activated macrophages in experimental parasitic infections by WGC Horsnell and F. Brombacher. pp 1 - 20 Research Signpost, 37/661(2) Fort, P.O. Trivandrum- 695 023 (2007), ISBN: 81-308-0166-3
A paradise for pathogens and parasites? F. Brombacher (2006), Crystal Ball:, Parasite Immunology, 28: 235-69.
Nieuwenhuizen, N., A. L. Lopata, M. F. Jeebhay, D. R. Herbert, T. G.Robins, F. Brombacher (2006). J Allergy Clin Immunol. 968-9 (I.F. = 9)
Interleukin 13, Editor F. Brombacher, (2003) Landes Bioscience, Georgetown, Texas, USA
